A 54-year-old man comes to the clinic for management of his gastroesophageal reflux disease (GERD). He is currently on cimetidine for his condition and reports that his GERD initially improved. However, following his recent move to Michigan, he is experiencing more frequent episodes of chest pain (4-5 times a week). The pain is described as burning in quality and is concentrated around his epigastric region following food ingestion. It does not radiate anywhere and is alleviated when he takes antacids. A physical examination demonstrates a healthy male with unremarkable findings. He is subsequently prescribed a new medication for control of his symptoms. What is the most likely mechanism of action of this new medication?
(A) Irreversible inactivation of cyclooxygenase enzyme
(B) Irreversible inhibition of H+/K+-ATPase at parietal cells
(C) Irreversible inhibition of histamine H2 receptors
(D) Reversible inhibition of H+/K+-ATPase at parietal cells
(E) Reversible inhibition of histamine H2 receptors
A 52-year-old woman presents with a complaint of headache for the past 10 days. Her headache is diffuse, dull in character, moderate in intensity, and is worse in the morning. It is not associated with fever and sensitivity to light or sound. She experiences occasional nausea but no vomiting. She did not have similar headaches in the past. Her blood pressure is 140/90 mm Hg; pulse, 60/min, and body mass index is 33.5 kg/m2. The neurological examination reveals normal extraocular movements. Mild bilateral papilledema is present. A magnetic resonance imaging of the brain reveals a solitary lesion in the left temporal region with predominant hemorrhage. Which of the following types of cancer has the highest tendency to cause this brain lesion?
(A) Breast cancer
(B) Lung cancer
(C) Melanoma
(D) Multiple myeloma
(E) Thyroid cancer
20-year-old male with muscle fatigue and vision problems. Based on the following information, please indicate the most likely diagnosis.
* Initial Evidence: fatigabilité_msk
* Clinical Evidence: ['atcdfam_mg', 'claud_mâchoire', 'diplopie', 'dysarthrie', 'dysphagie', 'dyspn', 'faiblesse_msmi', 'fatigabilité_msk', 'ptose', 'trav1_@_N']
(A) Myasthenia Gravis
(B) Guillain-Barré Syndrome
(C) Embolism
(D) Myocarditis
(E) Réaction dystonique aïgue
(F) OAP/Surcharge pulmonaire
(G) Fibrillation auriculaire/Flutter auriculaire
(H) Anémie
(I) Anaphylaxie
(J) Chagas
(K) Scombroïde